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NSAID‑Induced Ulcer Risk – Cannot Tolerate PPIs

Marsha has chronic arthritis and needs daily NSAIDs, but PPIs give her severe headaches. Her provider searches for alternative ulcer‑prevention strategies that won’t worsen her symptoms. Marsha wants to stay active without risking a GI bleed.

Question: How would you manage Marsha’s ulcer risk without PPIs?

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